Urinary Growth Hormone Measurement Usefulness As A Screening Test for Growth Hormone Deficiency

Urinary growth hormone excretion as a screening test for growth hormone deficiency.

Overnight urinary growth hormone secretion was measured by an immunoradiometric assay incorporating commercially available reagents, in 41 normal prepubertal school-children from three age groups: 3-5 years, 6-7 years, and 9-10 years. There was no significant difference between the groups expressing the results as total microU/specimen and so they have been combined to provide a prepubertal ref...

Urinary growth hormone estimation in diagnosing severe growth hormone deficiency.

Urinary growth hormone was measured in 54 children with short stature who had growth hormone deficiency that was initially diagnosed pharmacologically (arginine and L-dopa) and physiologically (mean growth hormone concentration during sleep evaluated twice). Based on the growth hormone response to pharmacological tests the subjects were subdivided into three groups: group A, 20 subjects with no...

Exercise as a screening test for growth hormone deficiency in children.

Lacey, K. A., Hewison, A., and Parlin, J. M. (1973). Archives of Disease in Childhood, 48,508. Exercise as a screening test for growth hormone deficiency in children. The serum growth hormone response to exercise has been evaluated in 98 children with short stature. In 65 children growth hormone deficiency was excluded by a single postexercise level of more than 20 mIU/ml. The test is simple an...

Urinary growth hormone excretion.

Adult growth hormone deficiency.

Growth hormone (GH) has an important physiological role in adulthood.1–3 Before the 1980s anecdotal reports suggested that patients lacking GH experienced symptoms of increased fatigue and low mood, features that improved with GH replacement.4 Long-term replacement was not considered because of the lack of availability of cadaveric GH. With the development of recombinant GH in the mid-1980s, in...